This research is one of many scientific attempts to better understand the specifics of telomere function and its effects on the cell growth. By understanding this relationship it becomes possible to understand the behavior of telomeres in the uncontrollable cell growth, which could be a step further in the understanding and the treatment of cancers. Some prior experiments revealed that some carcinogenesis (development of cancer) such as colorectal carcinogenesis are followed by the robust telomerase activity, which suggested the necessity of telomere lengthening for the progression of cancer. However, knocking out the telomerase gene and bringing thus the telomeres to their dysfunctional state, researchers discovered some very interesting trends in the growth of tumors. This research looks at the impact of such dysfunctional telomeres on the behavior of tumor cells.
They monitored the effects of different levels of telomere dysfunction on the growth and behavior of carcinomas in......
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