Jacob’s Syndrome
Jacob’s Syndrome is a rare chromosomal genetic syndrome where the male has an
extra Y male chromosome and ends up having 47 chromosomes with XYY instead of
normal 46,XY (male) or 46, XX (female.) It is very rare and happens in only
about 1 out of 1,000 men. The exact reason for this is unknown. In a very rare cases it was passed from father to son, but in most cases it is not hereditary. It was first
discovered by Patricia Jacobs in 1965. She proposed the suggestion that the
extra Y chromosome might lead to increased aggression in these men and might
land them in trouble with the law.
Usually this chromosomal change doesn’t cause any unusual physical features or
medical problems. 47,XYY boys and men are usually taller than average and
about seven centimeters taller than their parents and siblings. Bad acne was
noticed in very few early case reports, but dermatologists specializing in acne
now doubt that there's any relation between the two. Boys......
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