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Acetylsalicylic Acid Synthesis


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Experiment # 3
Acetylsalicylic Acid

Introduction: The purpose of this experiment is to create and isolate pure acetylsalicylic acid from the substances salicylic acid and acetic anhydride. Then one will find the melting point to determine purity.



Procedure: Make a hot bath. Weigh some salicylic acid and place in conical vial. Add .480mL of acetic anhydride and a drop of concentrated phosphoric acid. Drop in a magnetic spin vane and attach air condenser to vial. Partially submerge it in hot water. Stir with spin vane to dissolve salicylic acid. After mixture dissolves, heat for 8 to 10 minutes. Crystallize the Acetylsalicylic acid by cooling the mixture. Then add 3.0mL of water and stir.
Set up a Hirsh funnel for vacuum filtration. Add 1mL of cold water to help transfer all of crystallized substance. Rinse crystals with water once all collected in funnel. Let crystals dry in funnel. Let finish drying on a watch glass for the week. After a week take the product, and......

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Approximate Word Count: 640
Approximate Pages: 3 (260 words per double-spaced page)

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