‘There are three kinds of lies: lies, damned lies, and statistics.’ Benjamin Disraeli 1804 - 1881
‘Statistics: The only science that enables different experts using the same figures to draw different conclusions.’ Evan Esar 1899 - 1995
Has aprotinin still a place in cardiac surgery? The short answer is “yes.”
Perhaps the most controversial issue relating to cardiac surgery today relates the use of aprotinin. With all the recent information, one might well ask “Is there a place for aprotinin in current practice?”
A plethora of negative publicity has followed the publication in January 26, 2006 of an article in the New England Journal of Medicine. In a somewhat striking publication, it was accompanied by a wealth of venomous publicity in the lay press [1]. Additionally, legal websites touted for business. Mangano, using data collected from 1996 – 2000 (The McSPI EPI II database) reported an association of aprotinin use with an increase in mortality,......
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